Glucocorticoids should be used with caution in patients with what disease process?

Glucocorticoids, which are a class of steroid hormones, can significantly affect glucose metabolism and insulin sensitivity. In patients with diabetes mellitus, the administration of glucocorticoids can lead to increased blood sugar levels, complicating the management of their condition. This is particularly concerning as these medications can worsen glycemic control, potentially leading to hyperglycemia or diabetic ketoacidosis in susceptible individuals.

Due to this impact on glucose levels, healthcare professionals must exercise caution and closely monitor patients with diabetes mellitus when prescribing glucocorticoids. They may need to adjust the patient's diabetes medications or implement additional monitoring strategies to manage blood sugar levels effectively. Understanding this effect is crucial for ensuring safe and effective treatment in individuals with diabetes.