In what situation would the use of corticosteroids be contraindicated?

The use of corticosteroids is contraindicated in the presence of an active infection because these agents can suppress the immune response. Corticosteroids have anti-inflammatory and immunosuppressive properties, which can hinder the body’s ability to fight off infections. In situations where the body is already battling an active infection, the use of corticosteroids could allow the infection to worsen, as the weakened immune response may not effectively control the pathogen.

In contrast, corticosteroids can be beneficial in treating acute inflammatory conditions, managing symptoms in endocrine disorders, and providing relief in chronic pain syndromes. While caution is advised in these situations, especially regarding dosage and duration of treatment, they do not pose the same significant risk as they do with active infections.