What adverse reaction should be monitored in a client taking fludrocortisone?

Fludrocortisone is a synthetic corticosteroid that has mineralocorticoid properties, primarily used to help maintain sodium and fluid balance in conditions like Addison's disease or orthostatic hypotension. One of the known adverse reactions associated with fludrocortisone therapy is edema. This occurs because fludrocortisone promotes sodium retention and water retention, leading to increased fluid volume in the body. As a result, monitoring for edema is crucial in patients taking this medication, as excessive fluid retention can lead to complications like hypertension and heart failure.

While hypotension, dehydration, and insomnia are potential concerns with corticosteroid use, they are not the primary adverse effects directly associated with fludrocortisone. Understanding the drug's mechanism and its effects on fluid balance helps clarify why edema is the specific adverse reaction to watch for in patients receiving fludrocortisone therapy.