What assessment finding indicates a positive therapeutic response to mitotane therapy?

In the context of mitotane therapy, which is used primarily to treat adrenal cortex tumors, a positive therapeutic response can be assessed through various clinical indicators related to the patient’s physical capabilities and overall health status.

When a patient can lift 10 pounds, it suggests an improvement in their physical strength and functionality. Mitotane's primary action is to reduce cortisol production and inhibit adrenal function, which can lead to significant changes in a patient's vitality. An ability to lift weights indicates that the patient's strength and endurance have improved, potentially reflecting a reduction in symptoms associated with adrenal insufficiency or the complications from excess cortisol, which mitotane aims to manage.

While other options—like decreased dizziness, increased appetite, and changes in urination—can also indicate various aspects of health improvement, the ability to perform a physical task such as lifting weights is a more direct indication of therapeutic progress regarding strength and overall physical capability, essential metrics in evaluating the effectiveness of treatment for adrenal disorders.