What common side effect should the nurse warn a patient about when starting glucocorticoid therapy?

When starting glucocorticoid therapy, it is important for the nurse to warn the patient about weight gain as a common side effect. Glucocorticoids, such as prednisone and dexamethasone, can lead to increased appetite and changes in metabolism, prompting weight gain. Additionally, these medications may cause fluid retention, which can also contribute to an increase in weight.

Patients on glucocorticoids may experience changes in fat distribution, commonly leading to a rounded face ("moon facies") and increased fat deposits in the abdomen. Understanding this side effect helps prepare patients for what to expect and allows them to manage their lifestyle and dietary choices accordingly while on therapy.

Awareness of weight gain as a side effect can facilitate better patient monitoring and support, as well as its implications for long-term health if therapy is prolonged. Other potential side effects of glucocorticoids should also be communicated to the patient, but weight gain is particularly notable due to its prevalence and effects on patients' overall well-being.