What disease is a client on long-term glucocorticoid therapy at risk of developing?

Long-term glucocorticoid therapy is associated with an increased risk of developing osteoporosis. Glucocorticoids have several effects on bone metabolism, including reducing calcium absorption in the intestines, decreasing the formation of new bone, and increasing bone resorption. This can lead to a decrease in bone density, making bones more fragile and susceptible to fractures.

Patients on prolonged glucocorticoid therapy may also experience changes in hormone levels and a decrease in physical activity, both of which can further contribute to the loss of bone mass. It is essential for healthcare providers to monitor bone health in patients receiving long-term glucocorticoids and to discuss preventive measures, such as calcium and vitamin D supplementation, as well as lifestyle adjustments to help mitigate this risk.