What effect is NOT associated with mineralocorticoids?

Mineralocorticoids, such as aldosterone, primarily regulate electrolyte and water balance in the body. One of their main effects is to increase sodium reabsorption in the kidneys, which leads to increased water retention. This occurs because sodium reabsorption is closely linked to water retention; when sodium is reabsorbed, water follows osmotically, leading to increased blood volume and blood pressure.

Additionally, mineralocorticoids promote increased potassium excretion. This mechanism works because when sodium is reabsorbed, potassium is secreted into the renal tubules to maintain electrochemical balance, leading to its excretion.

While calcium retention is a function associated with other hormones, particularly parathyroid hormone and vitamin D, mineralocorticoids do not play a significant role in promoting calcium retention. Therefore, the effect that is not associated with mineralocorticoids is increased calcium retention. Instead, their primary roles focus on sodium and potassium dynamics, as well as water balance.