What reassurance can the nurse provide to a patient worried about body changes from Cushing's disease treatment?

The correct choice emphasizes that once treatment for Cushing's disease is effective, the soft tissue changes associated with the condition can indeed reverse. This aspect of the disease is particularly important, as Cushing's often leads to noticeable changes in appearance due to factors like fat redistribution, skin changes, and other metabolic impacts.

When the underlying hormonal imbalance caused by excess cortisol is addressed through appropriate treatment, such as surgery, medication, or radiation, patients often see significant improvements. For example, changes in skin thickness and discoloration may diminish, and fat can redistribute back to more typical areas of the body. The reassurance given to patients about the potential for these changes to improve with successful treatment can offer hope and motivation during a challenging time.

While other options may provide support in different ways—like addressing weight loss or psychological support—they do not directly relate to the physiological changes that can revert with treatment. Thus, highlighting the reversibility of soft tissue changes offers a more direct and encouraging response to the patient’s concerns.