Which assessment finding best indicates that fludrocortisone acetate is working?

Fludrocortisone acetate is a synthetic adrenocortical steroid that is primarily used for its mineralocorticoid effects, which include promoting sodium retention in the kidneys and regulating blood pressure. The effective assessment finding indicating that fludrocortisone acetate is working would be the measurement of blood pressure while in different positions, specifically sitting and standing.

When blood pressure readings are similar while sitting and standing, as demonstrated in the correct response, it suggests that the medication is effectively managing fluid balance and preventing orthostatic hypotension, a condition where blood pressure drops upon standing. This stability in blood pressure reflects proper sodium retention and adequate volume status, which are key indicators of the drug's efficacy.

In contrast, variations in blood pressure or the presence of pitting edema could signal inefficacy or complications related to treatment, such as fluid overload or ineffective blood volume regulation. Therefore, the consistency in blood pressure readings between these positions serves as the most reliable indicator of fludrocortisone action and its desired therapeutic effects.