Which potential side effect should nurses monitor in clients receiving glucocorticoid therapy?

When clients are receiving glucocorticoid therapy, one of the significant side effects that nurses should monitor for is hypertension. Glucocorticoids can cause sodium retention and fluid retention, leading to increased blood volume, which subsequently raises blood pressure. Over time, this can contribute to cardiovascular problems, making it essential for healthcare providers to regularly monitor blood pressure in patients on these medications.

In addition to hypertension, other potential side effects of glucocorticoid therapy include hyperglycemia, electrolyte imbalances, and changes in hydration status. However, monitoring for hypertension is particularly crucial, given its impact on long-term health outcomes and the risk of complications such as heart disease and stroke.