Which therapies are appropriate for a patient with Addison's disease?

In the management of Addison's disease, which is characterized by insufficient production of adrenal hormones, the primary treatment involves replacing the hormones that the adrenal glands are not producing adequately. Specifically, the replacement of mineralocorticoids is essential because patients with Addison's disease often experience deficiencies in aldosterone, which plays a crucial role in regulating sodium and potassium balance, as well as blood pressure.

The administration of mineralocorticoids, such as fludrocortisone, helps to restore this balance and correct the associated electrolyte imbalances and low blood pressure that may arise due to the lack of aldosterone. This therapy can significantly improve symptoms and enhance the quality of life for those afflicted with the condition.

While other hormone replacements may be relevant in different contexts, the primary and specific need in Addison's disease centers around mineralocorticoid replacement to address the core deficiencies of the disease.